Celiac disease is an autoimmune condition that prevents proper nutrient absorption and the digestion of?gluten.
The condition requires avoiding gluten to manage symptoms.
Signs and Symptoms of Celiac Disease
Signs and?symptoms of celiac disease vary widely from person to person. Indeed, some people with the condition are asymptomatic. Generally speaking, though, there are some telltale signs you should know.
- Abdominal pain,?bloating, or gas
- Chronic diarrhea (may be constant, or on and off for several weeks)
- Pale, foul-smelling, or?oily stool
- Nausea and vomiting
- Unexplained weight loss
Celiac disease can cause problems in other parts of the body, too. And some of these symptoms are more common in adults than in children.
- Anemia?(low red blood cell count)
- Fatigue (extreme tiredness that doesn't go away with sleep)
- Infertility or miscarriages
- Missed menstrual periods
- Depression or anxiety
- Canker sores?or?ulcers?inside the mouth
- Bone or joint pain
- Osteoporosis?(weak, porous bones that break more easily)
- Itchy, blistery?skin rashes
- Hair loss
- Tingling or numbness in hands or feet
Causes and Risk Factors of Celiac Disease
Unfortunately, researchers haven’t yet been able to identify exactly what causes celiac disease. Currently they think it has something to do with genetics combined with environmental factors.
How Is Celiac Disease Diagnosed?
A number of tests can help your doctor figure out whether you have celiac disease or another digestive condition.
- Blood tests?Your blood sample will be checked for special proteins called antibodies. Certain antibodies tend to be elevated in people with celiac disease. Before your?blood test, you should continue to eat foods containing gluten. Cutting out gluten before testing is complete could delay your diagnosis.
- Endoscopy?Your doctor may ask a gastroenterologist to perform an?endoscopy?to confirm your diagnosis if a blood test shows you may have celiac disease. You'll swallow a small, flexible tube containing a tiny camera. Through this tube, your doctor will perform a?biopsy, removing a tiny piece of tissue from the wall of your small intestine. A specialist (usually a pathologist) will view this tissue under a microscope to see whether it has been damaged by celiac disease.
- Genetic testing?Your doctor may order a genetic test to rule out a celiac disease diagnosis. Most people with celiac disease carry a certain variant of the HLA-DQ2 or HLA-DQ8 genes. But many people without celiac disease also have these variants, so celiac disease can't be diagnosed by genetic testing alone.
- Capsule endoscopy Your doctor may order this test, in which you swallow a tiny camera inside a small capsule that travels through your digestive tract. The camera takes thousands of photos that are transmitted and recorded.
Duration of Celiac Disease
Celiac disease is a lifelong disease and not something individuals can outgrow. People with the condition must stop eating gluten for the rest of their lives.
Treatment and Medication Options for Celiac Disease
You can ask your pharmacist if gluten is an ingredient in certain medicines, herbal supplements, vitamins, or minerals.
- Skin and hair products
- Toothpaste and mouthwash
- Communion wafers
- Glue on envelopes and stamps
You can never be too careful. Read ingredient labels carefully when you're out shopping and advise family and friends to do the same when shopping for you.
- Use food and product labels to identify ingredients that contain gluten
- Understand which foods are naturally gluten-free
- Find and eliminate?hidden sources of gluten from the diet
- Make healthy food choices
- Design meal plans
- After starting on a gluten-free diet, individuals with celiac disease will continue to see a doctor for periodic checkups to make sure the condition is improving. Many doctors recommend a follow-up visit four to six weeks after you start the diet, notes Coeliac UK.
Are There Supplements That Are Good for People With Celiac Disease?
A?multivitamin?or nutritional supplement can help you rebuild your levels of essential nutrients.
But keep in mind that some vitamins, minerals, and herbal supplements may contain gluten. Talk to your doctor or pharmacist before taking any nutritional supplement to make sure it doesn't contain gluten.
Can Medication Help Manage Celiac Disease?
A small percentage of people with celiac disease find that their symptoms don't improve, even with a strict gluten-free diet.
Steroids are typically taken for a short period of time to suppress the immune system and stop the body's harmful immune response.
How to Develop a Gluten-Free Diet to Control Celiac Disease
Foods to Avoid if You Have Celiac Disease
- Durum wheat
Some processed foods that may contain gluten include:
- Bouillon cubes
- Brown rice syrup
- Chewing gum
- Chips, including seasoned tortilla and potato chips
- Cold cuts, hot dogs, salami, and sausage
- Communion wafers
- French fries
- Imitation fish
- Rice mixes
- Soy sauce
- Beer and malt beverages
Cutting gluten out of your diet may seem like a difficult task, but many foods, including the following, are naturally gluten-free:
- Fresh cuts of meat and poultry
- Fish and seafood
- Beans, legumes, and nuts
Beware, though, that prepared or processed versions of any of the above foods, such as sausage or ice cream, may contain gluten.
Many gluten-free grains and starches can be substituted for wheat and other gluten-containing grains:
- Potato (but not potato chips)
- Gluten-free oats
- Nut flours
- Bean flours
Tips for Dining Out on a Gluten-Free Diet
The following strategies may help you stick to your gluten-free diet when eating out:
- Choose a restaurant with gluten-free options.?This means a place that serves naturally?gluten-free foods?or has a special gluten-free menu.
- Inform your waiter.?Let them know you have celiac disease and may get sick if you eat anything containing gluten, including flour, bread crumbs, or soy sauce. Also ask them to inform the chef or cook. This way, you’ll have more confidence that nothing on your plate has touched gluten.
- Ask questions.?Don't assume anything is gluten-free. Omelets, for instance, may have pancake batter added to the egg mixture to make them fluffier, and baked potatoes can be coated with flour to make the skins brown and crispy.
Prevention of Celiac Disease
At this time, there is no proven way to prevent celiac disease. The best way to keep symptoms of celiac disease under control is to maintain a gluten-free diet.
Complications of Celiac Disease
- Anemia (low red blood cell count)
- Osteoporosis (weak bones caused by loss of bone density)
- Infertility or miscarriage
- Peripheral neuropathy
- Liver problems
- Heart problems
- Certain cancers (intestinal?lymphoma, small bowel cancer)
- Lactose intolerance
- Dermatitis herpetiformis (an itchy rash of bumps and blisters) or other skin conditions
Research and Statistics: How Many People Have Celiac Disease?
Related Conditions and Causes of Celiac Disease
Unfortunately, celiac disease can be tough to diagnose in many people because its symptoms are often confused with those of other conditions. But it’s important to know that celiac is distinct from those conditions, including gluten intolerance and a?wheat allergy, because it's an autoimmune disease in which the immune system attacks the small intestine, leading to malabsorption.
Could Your Symptoms Be the Result of a Wheat Allergy?
If you’ve been tested for celiac and the results were negative, there’s a chance you simply have an allergy to wheat.
- Stuffy or runny nose
- Hives?or a skin rash
- Nausea and gastrointestinal symptoms, including diarrhea or vomiting
- Anaphylaxis?(though this is uncommon)
These symptoms may appear after you eat foods with wheat, including bread, cereal, or granola. Because these foods also contain gluten, a wheat allergy is commonly called a “gluten allergy,” though there’s actually no such thing.
Could You Have Intolerance to Gluten (Nonceliac Gluten-Sensitivity)?
Gluten intolerance, also called nonceliac gluten sensitivity (NCGS), is a possibility if you’ve tested negative for both celiac disease and a wheat allergy. But unfortunately, there isn’t a good test to diagnose this condition.
The main treatment for NCGS is a gluten-free diet, but as with celiac, be sure to work with your healthcare team to make sure you’re properly nourishing your body.
Celiac Disease and COVID-19
To date, there is no evidence or reports to suggest that individuals with celiac disease are at a greater risk of severe illness from?COVID-19?than those without the condition.
Resources We Love
To properly control celiac disease, you need more than just resources for recipes. By visiting websites such as?UpToDate, the?National Institute of Arthritis and Musculoskeletal and Skin Diseases National Resource Center, and the?U.S. Food and Drug Administration (FDA), you can find the resources you need to thrive with this autoimmune condition.
Additional reporting by Ashley Welch and Jane Okoji.
Editorial Sources and Fact-Checking
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